When Cuddy’s mother is admitted to Princeton Plainsboro and wants House off the case, House must come up with non-conventional methods to treat her. In the process he uncovers secrets which Arlene has hidden from Cuddy and her sister Lucinda. Meanwhile, House’s methods to treat Cuddy’s mother leads Masters to question her “by the book” stance on medicine, and Taub gets a second job from his ex-wife’s brother that takes a toll on him.